Tool Library Tool Information
Validation Information: FFQ (Dietary total antioxidant capacity)
Development and Validation of a Food Frequency Questionnaire for the Assessment of Dietary Total Antioxidant Capacity Frequency Questionnaire for the Assessment of Dietary Total Antioxidant Capacity
The total antioxidant capacity (TAC) of the diet may be an important tool to monitor the protective effect of plant foods in epidemiological studies. We developed a semi-quantitative FFQ for the assessment of dietary TAC by 3 different assays,
i.e., Trolox equivalent antioxidant capacity (TEAC), total radical-trapping antioxidant parameter (TRAP) and ferric reducing antioxidant power (FRAP). The FFQ consists of 53 questions about the major sources of dietary TAC in Northern Italy and was validated against a 3-d weighed food record (3D-WR) in 285 individuals (159 males and 126 females) aged 35–88 y and living in the province of Parma (Italy). Plasma TAC was also evaluated in a subgroup of subjects using the TEAC and FRAP assays. The FFQ was associated with 3D-WR (quadratic-weighted k ¼ 0.49 for TEAC, 0.53 for TRAP, and 0.49 for FRAP; P <0.0001) and proved reasonably accurate to classify individuals into quartiles of TAC intake. The FFQ had a good repeatability when re-administered after 1 y in 55 subjects (quadratic-weighted k for intertitle agreement ¼ 0.66 for TEAC, 0.70 for TRAP and 0.68 for FRAP; P < 0.0001). With both dietary instruments, the main contributors to TAC intake were coffee and tea in women and alcoholic beverages in men, followed by fruits and vegetables in both sexes. Plasma TAC and dietary TAC were not associated. In conclusion, our FFQ has the potential for being used to rank subjects on the basis of their antioxidant intake as determined by dietary TAC in large epidemiological studies. The FFQ should be validated in external populations before being used for research purposes.
Total number of nutrients validated: 0
Not all of the nutrients validated in the validation studies are included in the table below, as statistical data was only selected to be displayed for a number of nutrients, this included:
- Saturated Fat
- Mono-unsaturated Fat
- Poly-unsaturated Fat
- Non‐starch polysaccharides(NSP)
- Folic Acid
- Vitamin B12
- Vitamin C
- Fruit & Vegetables
- Urinary Nitrogen
To find information on the other validated nutrients please read the validation study.
- Macronutrients: 0
- Micronutrients: 0
|Comparator||Lifestage||Sex||Nutrient Measured||Mean Difference||Standard Deviation||Correlation Coefficient||Cohen's Kappa Coefficient||Percentage Agreement||Percentage Agreement Categories||Lower Limits of Agreement||Upper Limits of Agreement|
|Weighed Food Diary||Adults (aged 35-88 years)||Male Only||Fruits||-58.3 (Median)|
|Weighed Food Diary||Adults (aged 35-88 years)||Female Only||Fruits||-41.7 (Median)|
Some results have been calculated using statistical techniques based on the published data.
For further information on statistical terms click on Statistical tests used in validation studies
All correlations coefficients in the table are unadjusted unless stated otherwise. For adjusted correlation coefficients and other statistical methods used in the study e.g. paired t-tests, please read the validation articles.
- # Adjusted
- † Energy adjusted.
- ‡ For loge-transformed, energy-adjusted nutrient intakes.
- ^ Adjacent included.
- ᵟ Participants provided identical responses.
- (w) = Weighted.
Pellegrini N, Salvatore S, Valtuena S, Bedogni, G, Porrini M, Pala V, Del Rio D, Sieri, S, Miglio, C, Krogh, V, Zavaroni I & Brighenti F. Development and Validation of a Food Frequency Questionnaire for the Assessment of Dietary Total Antioxidant Capacity. (2007). The Journal of Nutrition.137. 93-98